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Fasting Can Improve Overall Health By Causing Circadian Clocks In the Liver and Skeletal Muscle To Rewire Their Metabolism, Study Finds (sciencedaily.com)
In a University of California, Irvine-led study, researchers found evidence that fasting affects circadian clocks in the liver and skeletal muscle, causing them to rewire their metabolism, which can ultimately lead to improved health and protection against aging-associated diseases. The study was published recently in Cell Reports. The research was conducted using mice, which were subjected to 24-hour periods of fasting. While fasting, researchers noted the mice exhibited a reduction in oxygen consumption (VO2), respiratory exchange ratio (RER), and energy expenditure, all of which were completely abolished by refeeding, which parallels results observed in humans.
"The reorganization of gene regulation by fasting could prime the genome to a more permissive state to anticipate upcoming food intake and thereby drive a new rhythmic cycle of gene expression. In other words, fasting is able to essentially reprogram a variety of cellular responses. Therefore, optimal fasting in a timed manner would be strategic to positively affect cellular functions and ultimately benefiting health and protecting against aging-associated diseases." This study opens new avenues of investigation that could ultimately lead to the development of nutritional strategies to improve health in humans. |
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| There are no conversations. |
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| cauz |
Jan. 16, 2019, 10:39 p.m. |
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| Jessa Gamble |
Life evolved under conditions of light and darkness, light and then darkness. And so plants and animals developed their own internal clocks so that they would be ready for these changes in light. These are chemical clocks, and they're found in every known being that has two or more cells and in some that only have one cell. |
| Roger Caras |
There are only three sins - causing pain, causing fear, and causing anguish. The rest is window dressing. |
| Drew Gilpin Faust |
As a scholar, you don't want to repeat yourself, ever. You're supposed to say it once, publish it, and then it's published, and you don't say it again. If someone comes and gives a scholarly paper about something they've already published, that's just terrible. As a university president, you have to say the same thing over and over and over. |
| Joyce Banda |
Overall, I have formed three major organizations: the National Association of Business Women, the Young Women's Leaders Network, and the Joyce Banda Foundation. Under the foundation, we have a huge program that targets women to teach them about HIV and other diseases and to give them economic empowerment. |
| Elton Gallegly |
Instead, California is one of only 10 states that provides in-state college and university tuition to illegal immigrants. That's grossly unfair to a legal high school student who moves out of California for a year, then returns to attend college. |
| Michele Bachmann |
Where do we say that a cell became a blade of grass, which became a starfish, which became a cat, which became a donkey, which became a human being? There's a real lack of evidence from change from actual species to a different type of species. |
| Umberto Eco |
The book is like the spoon, scissors, the hammer, the wheel. Once invented, it cannot be improved. You cannot make a spoon that is better than a spoon... The book has been thoroughly tested, and it's very hard to see how it could be improved on for its current purposes. |
| Dianne Feinstein |
It is my hope that the number of stem cell lines available for federally-funded research will be expanded so that the government can continue to participate in this vital research and provide hope to the millions of Americans with diseases that might be cured. |
| G. Stanley Hall |
Civilization is so hard on the body that some have called it a disease, despite the arts that keep puny bodies alive to a greater average age, and our greater protection from contagious and germ diseases. |
| Mike Ferguson |
America's doctors, nurses and medical researchers are the best in the world, but our health care system is broken. |
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No Healthy Level of Alcohol Consumption, Says Major Study (theguardian.com)
Even the occasional drink is harmful to health, according to the largest and most detailed research carried out on the effects of alcohol, which suggests governments should think of advising people to abstain completely. The uncompromising message comes from the authors of the Global Burden of Diseases study, a rolling project based at the University of Washington, in Seattle, which produces the most comprehensive data on the causes of illness and death in the world. Alcohol, says their report published in the Lancet medical journal, led to 2.8 million deaths in 2016. It was the leading risk factor for premature mortality and disability in the 15 to 49 age group, accounting for 20% of deaths. The study was carri...
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Sleep Deprivation Disrupts Brain-Cell Communication, Study Finds (npr.org)
A new study published in the journal Nature Medicine found that sleep deprivation causes the bursts of electrical activity that brain cells use to communicate to become slower and weaker. "The finding could help explain why a lack of sleep impairs a range of mental functions, says Dr. Itzhak Fried, an author of the study and a professor of neurosurgery at the University of California, Los Angeles," reports NPR. From the report:
The finding comes from an unusual study of patients being evaluated for surgery to correct severe epilepsy. As part of the evaluation, doctors place wires in the brain to find out where a pat...
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As a cell biologist, Sundar Balasubramanian never forgot his rural southern Indian roots, or the traditional practices his uncle, the village healer, exposed him to. Today, as a researcher and assistant professor at the Medical University of South Carolina, Balasubramanian has turned his focus back to those roots — specifically, to pranayama, a deep-breathing relaxation technique. He’s showing that this ancient yoga practice is about more than relaxing — it can change us at the cellular level.
Q: What made you examine this technique through a cellular biology lens?
A: In 2005, I noticed whi...
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Microplastics Found In 90 Percent of Table Salt (nationalgeographic.com)
New research shows microplastics in 90 percent of the table salt brands sampled worldwide. Of 39 salt brands tested, 36 had microplastics in them, according to a new analysis by researchers in South Korea and Greenpeace East Asia. Salt samples from 21 countries in Europe, North and South America, Africa, and Asia were analyzed. The three brands that did not contain microplastics are from Taiwan (refined sea salt), China (refined rock salt), and France (unrefined sea salt produced by solar evaporation). The study was published this month in the journal Environmental Science & Technology.
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Study of Cellphone Risks Finds 'Some Evidence' of Link To Cancer, At Least In Male Rats (nytimes.com)
For decades, health experts have struggled to determine whether or not cellphones can cause cancer. On Thursday, a federal agency released the final results of what experts call the world's largest and most costly experiment to look into the question. The study originated in the Clinton administration, cost $30 million and involved some 3,000 rodents. The experiment, by the National Toxicology Program, found positive but relatively modest evidence that radio waves from some types of cellphones could raise the risk that male rats develop brain cancer. But he cautioned that the exposure levels and durations were far greater than what people typically encounter, and thus cannot "be compared...
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Honeybees Seem To Understand the Notion of Zero, Study Finds
A new study published in the journal Science finds honeybees are able to understand the concept of zero numerosity, joining the ranks of dolphins, parrots, and primates. Sci-News.com reports:
The study authors set out to test the honeybee on its understanding, marking individual honeybees for easy identification and luring them to a specially-designed testing apparatus. The bees were trained to choose an image with the lowest number of elements in order to receive a reward of sugar solution. For example, the bees learned to choose three elements when presented with three vs. four; or two elements when presented with two vs. thre...
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Over 30,000 Published Studies Could Be Wrong Due To Contaminated Cells
Researchers warn that large parts of biomedical science could be invalid due to a cascading history of flawed data in a systemic failure going back decades. A new investigation reveals more than 30,000 published scientific studies could be compromised by their use of misidentified cell lines, owing to so-called immortal cells contaminating other research cultures in the lab. The problem is as serious as it is simple: researchers studying lung cancer publish a new paper, only it turns out the tissue they were actually using in the lab were liver cells. Or what they thought were human cells were mice cells, or vice versa, or something else entirely. If you think that sounds bad, you're right, as it means the findings o...
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Alcohol Can Cause Irreversible Genetic Damage To Stem Cells, Says Study (theguardian.com)
A new study, published on Wednesday, states that drinking alcohol produces a harmful chemical in the body which can lead to permanent genetic damage in the DNA of stem cells, increasing the risk of cancer developing. From a report:
The research, using genetically modified mice, provides the most compelling evidence to date that alcohol causes cancer by scrambling the DNA in cells, eventually leading to deadly mutations. During the past decade, there has been mounting evidence of the link between drinking and the risk of certain cancers. "How exactly alcohol causes damage to us is controversial," said ...
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Scientists Reawaken Cells From a 28,000-Year-Old Mammoth
Cells from a woolly mammoth that died more than 28,000 years ago have been partially reactivated inside of mouse egg cells, according to a study published Monday in Scientific Reports. "The achievement shows that biological activity can be induced in the cells of long-dead creatures, but that does not mean that scientists will be resurrecting extinct animals like mammoths any time soon," reports Motherboard. From the report:
A team led by Kazuo Yamagata, a biologist at Kindai University in Japan, extracted cells from the remains of "Yuka," a young female mammoth discovered in 2010 on the coast of the Dmitry Laptev Strait in the Russi...
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"Daily exposure to BPA in amounts that are FDA-approved to be “safe” may still be altering insulin release and be enough to have implications for the development of Type 2 diabetes and other metabolic diseases, finds the first study of its kind."
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